How does aneuploidy lead to cancer initiation?

Answers

Answer 1

Answer:

Chromosomal aberrations during cell division represent one of the first recognized features of human cancer cells, and modern detection methods have revealed the pervasiveness of aneuploidy in cancer. The ongoing karyotypic changes brought about by chromosomal instability (CIN) contribute to tumor heterogeneity, drug resistance, and treatment failure. Whole-chromosome and segmental aneuploidies resulting from CIN have been proposed to allow “macroevolutionary” leaps that may contribute to profound phenotypic change. In this review, we will outline evidence indicating that aneuploidy and CIN contribute to cancer evolution.


Related Questions

the break dawn of food starts from our mouth due to the process of _________,_________and __________?​

Answers

saliva, esophagus and stomach?

What do mitochondria make?

Answers

Answer:

It produces energy for the cell. That energy is called ATP or adenosine triphosphate

Explanation:

Answer:

Mitochondria are membrane bound cell organelles mitochondrion singular that generate most of the chemical energy needed to power the cell's biochemical reactions Chemical energy produced by the mitochondria is stored in a small molecule called adenosine triphosphate ATP

Hope this helps!

Why do whales need oxygen?

Answers

Whales need oxygen for respiration processes because they do not have gills, and whales are unable to breathe oxygen that is dissolved in water.

The lack of gills, which prevent whales from breathing oxygen dissolved in water, is the most obvious distinction between whales and other fish. Instead, they have lungs, which means that whenever they want to breathe air, they have to come to the surface.

They can stay underwater for hours at a time because they have a very efficient respiratory system that allows their lungs to get the most out of each breath. To put things in perspective, when we are at rest, humans breathe about 12 to 20 times per minute, but they only take in 5% of the oxygen in a single breath. This is in contrast to a whale, which can absorb up to 90% of the oxygen it breathes. This indicates that a whale takes in significantly more oxygen in a single breath than a human does.

Know more about Respiration here: https://brainly.com/question/12605249

#SPJ4

What are some evidences that support evolution?

Answers

some evidences that support evolution are: anatomy, molecular biology, biogeography, fossils, & direct observation. Genes, which are passed from parent to kid during reproduction, express themselves in these traits.

Evolution is the gradual change in the hereditary characteristics of biological populations over many generations. Genetic recombination and mutation are the usual causes of variation within a population. Genetic drift and natural selection, two evolutionary processes that might lead to particular traits becoming more or less dominant in a population, are likely to occur in this variation. This is how evolution works. Heritable traits emerge over multiple generations in response to shifting evolutionary factors that determine whether a trait is prevalent or rare within a population.

To learn more about Evolution click on the given link: https://brainly.com/question/29351017

#SPJ4

Which of the following is driven by
energy from gravity?
A. Precipitation
B. Evaporation
C. Condensation
D. Crystallization

Answers

I believe it’s A. Precipitation

It is precipitation that is caused by the energy driven from gravity. The correct answer is option A.

What is crystallization ?

It is making up of crystals that is the hardened structures that may or may not have the definite structures and shapes from the liquid.

From the clouds under the impact of gravity the water falls down and flow downward towards the shed and flow in downward direction. Energy from the sun and the water cycles continue these cycles.  

Precipitation comes up when the water gets condensed in the clouds and the water gets flown away from the clouds when evaporation. when the drops are heavy and they fall on Earth in the downward direction.

Precipitation is causing the condensation of clouds and the latter later forms the clouds via the process of precipitation of it falls down.

Learn more about precipitation at :

https://brainly.com/question/18109776

#SPJ2

Based on the movie( Food Inc), what are examples of policies that have been proposed as ways of dealing with social
changes resulting from new technologies, such as genetically engineered plants and animals.

Answers

Answer:

Food, Inc. Summary

If you aren’t completely familiar with what it is, Food, Inc was created by documentary filmmaker Robert Kenner and narrated by Eric Schlosser (Fast Food Nation), and also features commentary from Michael Pollan (The Omnivore’s Dilemma).

It lifts the veil on how the nation’s food industry has been consumed by corporations and how that impacts the farms where our food comes from, the supermarkets where we buy our food, and the restaurants where we eat that food. It tackles the FDA, food safety, food production, large-scale animal processing plants, and other food matters. If you are at all concerned or curious about the state of food supply in America, you should watch Food, Inc.

The Key Takeaways from the Movie

Supermarkets and Corn

The tomatoes you buy in the grocery store are picked when green and then ripened with ethylene gas

The food industry doesn’t want you to know the truth about what you are eating because if you did you might not eat it—it is a world deliberately hidden from us

Most people have no idea where their food comes from (do you?)

The fact that people need to write a book (and a blog!) telling people where their food comes from shows how far removed we are

The average grocery store has 47,000 products which makes it look like there is a large variety of choices—but it is an illusion—there are only a handful of corporations (like Monsanto, Tyson, and Perdue for example) and a few major crops involved

So much of the processed food is just clever rearrangements of corn (here are just a few examples of the additives that are derived from corn: cellulose, saccharin, polydextrose, xanthan gum, maltodextrin, and my favorite—ha ha ha—high fructose corn syrup)

30% of our land base in the US is used to grow corn because thanks to government policy farmers are paid to overproduce this easy-to-store crop

Farmers are producing so much corn that food scientists had to come up with uses for it—just like some of the additives listed above

Food scientists have also spent a lot of time reengineering our foods—so they last longer on grocery store shelves and don’t get stale

At the supermarket, candy, chips, and soda are all cheaper than produce

A double-cheeseburger from McDonald’s is 99 cents and you can’t even get a head of broccoli for that price

Those snack calories are cheaper because the commodity crops like corn, wheat, and soybeans are heavily subsidized

You start feeding corn to cows, E. Coli evolves and a certain mutation occurs which is very a harmful bacteria

Animals at factory farms stand ankle deep in their manure all day long so if one cow has E. Coli others can get it too

At a slaughterhouse their hides are caked with manure and if you are slaughtering 400 cows per hour how do you keep it from spreading?

So these harmful new strains of e Coli, that didn’t use to be in the world, are now a problem

E. Coli is even in spinach and apple juice because of the runoff from factory farms

It doesn’t help that the Chief of Staff for the USDA was a former lobbyist for the beef industry

Regulatory agencies are being controlled by the very companies they are supposed to be scrutinizing

There has always been food poisoning, but food is not getting safer it is becoming more contaminated because with the bigger factories it spreads the problem far and wide

There are only 13 slaughterhouses for the majority of beef in all the US

Ground beef from the grocery store has thousands of different cows mixed up in it so the chance of one of those cows in your meat having a disease is increased

After eating hamburger contaminated with E. Coli 0157:H7 a woman’s 2-year-old son went from a perfectly healthy boy to being dead in 12 days

In the 90’s some industrial meat factories were tested for E. Coli 0157:H7 and if they failed they were supposed to be shut down—but there was not enough authority to close the contaminated plants

Some companies are now using a hamburger meat filler cleansed with ammonia hydroxide to help kill E. Coli (mmm…that sounds tasty)

Plz help , trying to fix grade

Why do gametes have half a set of DNA? What would happen if they had afull set of DNA? Explain your answer.

Answers

Answer:

What would happen if gametes had a full set of DNA? The number of DNA strands would double with each generation. One gamete cell divides into four cells, but each resulting cell has half the amount of DNA as compared to the original cell. Body cell mitosis

Explanation:

In what organisms does alcoholic fermentation take place?

A. viruses
B. fruit flies
C. yeast and some bacteria
D.plants

Answers

C. yeast and some bacteria

Answer:

Yeast and some bacteria.

Explanation:

My sister used to make homeade kombucha, which is a tea/drink made with bacteria that grows over time. it is indeed made with alcohol, but keep in mind that yeast is a living organism, and it is in some alcohols like wine and beer.

Hypothetically, if a whole population was identical, could it evolve and why?

Answers

No because of the whole population was identical they would not have genders and would not be able to reproduce. Reproduction is essential to evolution

Which describes a common pathway of nerve impulses through the divisions of the nervous system?

Answers

Answer:

Sensory Neurons

Explanation:

please help fast!!!! the main carbohydrates found in our food are in the form of _____ and _____. its from grade 6th chapter 2 components of food 50 points

Answers

Answer:

tod sun a qu e sjjee'

Explanation:

wins uend de iue dnauw oiptua hagnte pao

Answer:

starch and sugar

hope it helps

please mark Brainliest

if a cell contained three pairs of homologoues (n=3, 2n=6) how many configurations are possible?

Answers

Twice the number of chromosomes in a haploid cell (n).

How many chromosomal combinations are feasible in the gametes of a 2n 6 cell?

The number of potential chromosomal pairings in gametes is 2n (two to the ‘n’ power, where ‘n’ is the number of chromosomes in the haploid set). So, for 2n = 4, n = 2, and gamete number = 22 = 4, the answer is 4. Furthermore, for 2n = 6, n = 3, and gamete number = 23, the answer is 8.

As a result, an organism with cells 2n=6 is diploid and contains 6 chromosomes in total. In other words, this creature contains three chromosomal pairs. We will use the formula nCr = n! / r! * (n – r)! to compute combinations, where n represents the total number of things and r indicates the number of items picked at a time.

To learn more about chromosomal to refer:

https://brainly.com/question/1596925

#SPJ1

What are the conclusion from Mendelian experiment?

Answers

Mendel gathered his data for tens of thousands of plants before coming to the conclusion that the traits might be divided into expressed and latent features. These traits were described by him as being dominant and recessive, respectively. In a hybridization, dominant features are those that are passed on unaltered. 

The three laws of dominance, independent assortment, and segregation serve as a summary of all the findings of Mendel's experiment. He proposed that each gene be passed down to the organisms twice, once from each parent. In their gametes, organisms only share one copy of each gene. In his opinion, traits are discretely inherited from each parent, one at a time.

To know more about the Mendelian experiment please visit

https://brainly.com/question/29679846

#SPJ4

why are melting glaciers dangerous for humans

Answers

it can affect electricity and cause a shortage. along with that, if a glacier flows across a stream/river , it’ll create a dam that stores a lot of water. therefore, it could end up flooding an area
Flooding caused by a glacier
More dangerous is the case when a glacier flows across a stream or river, creating a dam that can trap a large amount of water. ... In Peru in 1941, 6,000 people perished when a glacial lake suddenly burst through its dam, flooding the town of Huaraz below it.

Which of the following is a cause of the ocean levels periodically rising and then falling?
A The slight tilt of the Moon
B The force of gravity from the Moon
The convection within Earth's mantle
The revolution of Earth around the Sun.

Answers

Answer: B

Explanation:

The answer is b hope this helps

‼️‼️Help me out pls‼️‼️
Describe one human impact that is harmful to the environment AND one that is beneficial. Describe how each of these actions impacts biodiversity.

Answers

Answer:

one thing that is harmful is pollution. it kills lots of sea life and harming out air. a way we can pollute in a helpful way is to only throw things on the ground that is biodegradable and not plastic

Oxpecker birds eat ticks and other
parasites that live on the skin of
rhinoceroses. This is an example of

Answers

Answer:

mutualistic relationship

Explanation:

Best Question/Problem for Hot and cold compress

helpp mee plsss Thank youu

Answers

Im guessing any is fine, as long as its acceptable.

"What are the benefits and potential risks of using hot and cold compresses, and when is it appropriate to use each type?"

describe how the respiratory areas maintain a normal breathing pattern

Answers

The respiratory system is responsible for maintaining a normal breathing pattern by bringing oxygen into the body and removing carbon dioxide. This process is controlled by the brainstem.

How to describe the respiration?

The brainstem sends signals to the muscles of respiration, including the diaphragm and the intercostal muscles. The diaphragm is the main muscle used for breathing and contracts during inhalation, causing the lungs to expand and fill with air.

The intercostal muscles, located between the ribs, also contract during inhalation to lift the ribcage and increase the volume of the thoracic cavity. During exhalation, the diaphragm and intercostal muscles relax, and the lungs deflate, pushing air out of the body. The rate and depth of breathing are also regulated by a complex network of nerve cells in the brainstem that respond to changes in blood oxygen and carbon dioxide levels, as well as to other physiological and psychological factors.

Learn more about respiration on;

https://brainly.com/question/3246071

#SPJ1

Theobroma cacao (cacao) is the tree that produces seeds that are turned into chocolate. These trees provide many poor people in the tropics with some cash income. However, these farmers face many obstacles to production of their crop, including temperature and rainfall changes caused by atmospheric CO2 increases, and many diseases and pests. Analysis of the cacao genome showed that there is some (but not a lot) of genetic variation in the 10 major varieties. Which of the following strategies would be most useful in the long term in reducing pressures faced by cacao farmers? Select one:
A. Fertilize the trees in closely spaced areas and add fungicides and pesticides to eliminate pests.
B. Plant more trees in the temperate zone.
C. Plant trees farther apart so that disease transmission rates from one tree to the next will be lower.
D. Crossbreed cacao strains that produce high-quality cacao beans and ones resistant to a disease. Clear my choice

Answers

Answer:

B. Plant more trees in the temperate zone.

Explanation:

The presence of abundant cabondioxide (CO2) in the atmosphere is as result of a decrease in plants populations.

plants makes use of CO2 in photosynthesis a process in which green plants manufacture their food Abundance of trees helps to clear the environment from excess CO2 through their utilization leading to a fresh and enabling environment.

Hence their is need to plant more trees in temperate and avoid deforestation of trees to enable plant make of CO2 and reduced the adverse effect of its excess in the environment.

Can any body help me out please:) thank you!

Answers

Answer:

All answers are in the image

Can someone please answer these for me

Answers

Answer:

1. genotype of female: Bb

a. genotype of male: bb

b. white is dominant

c. female phenotype: white

male phenotype: black

Where is the most ATP produced in cellular respiration ?

Answers

The majority of ATP created during cellular respiration is used in the electron transport chain (oxidative phosphorylation).

Cellular respiration is the mechanism by which glucose molecules are broken down into [tex]CO_2[/tex] and [tex]H_2O[/tex] to provide energy from Adenosine Triphosphate (ATP). Additionally, cellular respiration often occurs in an organism's cells by turning the metabolic energy contained in foods into adenosine triphosphate. Additionally, it occurs in three steps, which are the TCA cycle, electron transport, and glycolysis (Oxidative phosphorylation). As a result, the stage of aerobic cellular respiration that produces the most ATPs is called oxidative phosphorylation.

Normally, ATP releases energy by dismantling any weak phosphate cells that may be present. The energy that is released as the phosphate cell disintegrates is then put to use. ADP is created after ATP.

For more such question on ATP produced.

https://brainly.com/question/787522

#SPJ4

please help me, I'm from Vietnam you can translate

Answers

Answer:

What does it say? I can't read it well

Explanation:

The sequence of one strand of DNA is ACCTGC. What is the sequence of the complimentary strand of DNA

Answers

The complimentary strand is:
TGGACG

Remember, A pairs with T and T pairs with A. G pairs with C and C pairs with G.

What is insertion and deletion called?

Answers

An insertion and deletion is called as a frameshift mutation .

An insertion is a point mutation in which one or more base pairs is added to a DNA sequence. Point mutations is further divided into silent mutations, missense mutations, and nonsense mutations.

Frameshift mutation is considered as a genetic mutation caused by a deletion or insertion in a DNA sequence. This kind of mutation shifts the way the sequence is read. diseases like cystic fibrosis is a result of frameshift mutation that alters the CFTR gene. The harshness of frameshift mutation is reliant on the number of nucleotides and the position of insertion of nucleotides.

To learn more about Frameshift mutation , here

brainly.com/question/14364090

#SPJ4

How does Mendelian genetics apply to humans?

Answers

Mendelian inheritance is the term used to describe how qualities that are regulated by a single gene with two alleles, one of which may be dominant to the other, are passed down from parent to child. Even though just a few human features are governed by a single gene with two alleles, they provide a solid foundation for learning about human heredity. 

He came to the conclusion that each parent transmits a pair of distinct genes to their offspring. Mendel studied how parental genes diverged and whether they manifested in the offspring as dominant or recessive traits. He was familiar with the mathematical traditions that were passed down from one generation to the next. Mendel's approach created a genetics template that is still employed today for gene discovery and comprehending the genetic characteristics of inheritance.

To know more about genetics please visit

https://brainly.com/question/13049663

#SPJ4

Structures as different as human arms, bat wings, and dolphin flippers contain many of the same bones, which develop from similar embryonic tissues. These structural similarities are an example of ________. Structures as different as human arms, bat wings, and dolphin flippers contain many of the same bones, which develop from similar embryonic tissues. These structural similarities are an example of ________. the evolution of similar appearance as a result of common function homology the evolution of common structure as a result of common function convergent evolution

Answers

Answer:

homology.

Explanation:

These similarities in structural are an example of homology because human arms, bat wings, and dolphin flippers are different organisms that have the common ancestor. The similar bone structure of different organisms and different its function is due to common ancestor. Homology similarity of the structure and physiology of different species of organisms due to their descent from a common evolutionary ancestor so we can say that these structural similarities are an example of homology.

Which set of conditions would most likely cause a change in gene frequency in a population that reproduces sexually

Answers

Small population size is most likely to result in changes in allele frequencies in a population. So, the correct option is (B).

The relative frequency of an allele (gene variant) at a specific locus in a population, expressed as a fraction or percentage, is known as allele frequency or gene frequency. It is the proportion of all chromosomes in the population that carry that allele divided by the entire population or sample size. Microevolution is the change in allele frequencies that happens within a population over time.

Given the given facts:

A specific location on a chromosome and a specific allele at that siteA population of N people with ploidy n, which means that each person has n copies of each chromosome in their somatic cells (e.g. two chromosomes in the cells of diploid species)In the population, the allele is found on I chromosomes.

Learn more about   gene frequency to visit this link

https://brainly.com/question/13798929

#SPJ4

Full Question: Which set of conditions would most likely cause a change in gene frequency in a population that reproduces sexually A. random mating. B. Small population size. C. No migration into or out of a population. D. Absence of natural selection

Capillary action, which allows plant sap to flow through a tree, is the result of cohesion between water molecules. True False

Answers

Capillary action happens in light of the fact that water is tacky, on account of the powers of attachment (water particles like to remain nearby) and bond (water atoms are drawn in and stick to different substances).

The development of water particles in the plant body is because of the cement powers between the water atoms and surfaces of the root and stems. The durable powers present between the water particles keep them intact and back off their transportation.

Since water particles like to remain together (attachment) and like to adhere to the walls of the containers of cellulose (bond), they ascend the cylinders as far as possible from the roots to the leaves. Water then, at that point, dissipates from the leaves, assisting with drawing up additional water from the roots. This interaction is called hairlike activity.

To learn more about Capillary here

https://brainly.com/question/83042

#SPJ4

Other Questions
Complete the equation of the line whos y intercept is (0,-1) and slope is 4 which operation should be completed first to find the value of the expreesion below 12 + 30 / (6 -3) + 1 Fill in the blank.When using a graduated cylinder you must look at ________ of the liquid when taking readings. Read the sentences below. Determine if the sentences are written correctly or if there is a fragment or run-on sentence. Lake Superior is one of the w Colleges and universities have historically used graduation ceremonies to launch what type of campaigns What were two benefits of the British rule over India? which word combination is an antonym for a significant amount Decide whether the sentence is correct or incorrect as written. Quera decirte algo importante. Correct incorrect II. Rewrite the given sentences in their present continuous2. Rahul receives an award on the children's day. Please Help! Need this to pass :/ Compare and contrast the two types of people Gray describes in Elegy in a Country Churchyard. Full credit answers will include description of the two types of people and include details to show how they compare and contrast. Pleaseeeee help Rewrite each sentence. Change the noun word to a pronoun.1. Karen made dinner for the whole neighborhood.2. Tommy played football with Miguel and Ramon.3. Mr.Rivera went to the movie with Mrs.Bustelo.4. The car needs to be fixed. Choose whether the pair of words are similar or opposite in meaning,gaseosa/refrescoA. similarB. opposite How can literature help us develop the critical thinking skills needed to participate wisely in local, national, and global communities? Where do most Republican states seem to cluster in the United States?O A. Scattered throughoutOB. The coastsO C. The interiorD. In the South Does anybody know what the answer to this question? Select all ratios equivalent to 2:14. A3:21b.1.2.c16:112 im so bad at this help plss I should have done homework or studied instead/ but I got up on the wrong side of the bed. What dose this mean Find my number, if the product of my number and 3 is 15 more than the sum of my number and 3