The pulmonary arteries differ in structure from the arteries of the systemic circulation system in several ways. The walls of pulmonary arteries are thinner and less muscular compared to systemic arteries.
They have a smaller diameter and are more compliant, allowing for easier expansion and accommodating changes in blood flow. This difference in structure is crucial for blood pressure in the lungs. The pulmonary arteries transport deoxygenated blood from the right ventricle of the heart to the lungs for oxygenation. The thinner walls and lower resistance in the pulmonary arteries help maintain lower blood pressure in the lungs.
The structural differences in the pulmonary arteries ensure that blood flow in the lungs is optimized for gas exchange while preventing excessive pressure that could compromise lung function. The lower blood pressure in the pulmonary circulation allows for efficient oxygenation of blood and facilitates the exchange of carbon dioxide during respiration.
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Draw the voltage changes you expect (graph Vm vs. time) to occur after you inject a current to bring a neuron up to what normally be threshold, but in your case voltage-gated Na+ channels open slower than voltage-gated K+ channels. Explain your diagram in a few sentences.
In the given scenario where voltage-gated Na+ channels open slower than voltage-gated K+ channels, the expected graph of Vm (membrane voltage) versus time would exhibit a different pattern compared to the typical neuronal threshold response.
What is the expected voltage response (Vm vs. time) when voltage-gated Na+ channels open slower than voltage-gated K+ channels after injecting a current to bring a neuron up to threshold?
Initially, upon injecting the current, the membrane voltage (Vm) would start to increase gradually due to the activation of voltage-gated K+ channels, which have a slower response compared to the Na+ channels.
As the K+ channels open, they allow K+ ions to move out of the cell, leading to an outward current and causing a slight decrease in Vm.
However, since the voltage-gated Na+ channels open slower in this case, the rapid influx of Na+ ions that usually occurs during the threshold phase would be delayed.
As a result, the membrane voltage would continue to rise gradually until the slower-opening Na+ channels eventually reach their activation state. Once the Na+ channels open, there would be a rapid depolarization phase where Vm sharply increases due to the influx of Na+ ions.
Overall, the graph of Vm versus time would show a gradual increase followed by a rapid depolarization, reflecting the delayed opening of Na+ channels relative to the slower-opening K+ channels.
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Fluid excess can happen when large amounts of _________ and ________ are lost but just replaced by plain water. a. BPH, bicarbonate ions b. salt substitute, lipid molecules c. water, sodium d. hemoglobin, carbon dioxide
Neurons supplying smooth muscle a. display swellings called varicosities b. display receptors only on the dendrites c. create precise neuromuscular junctions with each myocyte d. secrete histamine
During fat absorption, where are the triglycerides combined with phospholipids and cholesterol? a. in the rough endoplasmic reticulum b. in the Golgi apparatus c. in a temporary vesicle d. in the mitochondria
c) Fluid excess can happen when large amounts of water and sodium are lost but just replaced by plain water.
Fluid excess can occur when large amounts of water and sodium are lost but only replaced by plain water. In the body, water, and sodium play crucial roles in maintaining fluid balance. When excessive water is lost through processes such as sweating or excessive urination, and only plain water is consumed without adequate sodium intake, it can lead to an imbalance in fluid levels. Water is an essential component for hydration, while sodium is an electrolyte that helps regulate fluid balance and osmotic pressure. When there is an insufficient intake of sodium to match water loss, the body may retain excess water, resulting in fluid excess or hyponatremia. To maintain fluid balance, it is important to replace not only water but also electrolytes like sodium when there is a significant fluid loss to avoid imbalances and promote proper hydration.
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The human catalase functions best at a ph of 7 and the stomach enzyme pepsin functions at a ph of 2. why the difference?
The human catalase and the stomach enzyme pepsin have different optimum pH ranges because each enzyme has evolved to work best under different environmental conditions.
The human catalase enzyme is found mainly in the liver and other organs, and it works best at a pH of 7, which is close to the neutral pH of blood. Catalase plays a vital role in breaking down hydrogen peroxide into water and oxygen, which is an essential reaction for cells because hydrogen peroxide is a toxic byproduct of cellular respiration. Since blood has a pH of 7.4, it makes sense that catalase would function best at a pH close to this value, allowing it to efficiently detoxify cells without causing any damage.
The stomach enzyme pepsin, on the other hand, is found primarily in the stomach, where it helps to break down proteins into smaller peptides. The stomach is an acidic environment, with a pH of 2, due to the production of hydrochloric acid. Pepsin is adapted to work best at a low pH, allowing it to function effectively in the stomach's harsh environment and catalyze the hydrolysis of proteins. Therefore, the human catalase functions best at a pH of 7, while the stomach enzyme pepsin functions at a pH of 2 due to their different environmental requirements.
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Mary, a 13-month-old baby, was taken to the ER for vomiting for the past 3 days. Upon examination Mary was irritable, and tachycardic. Her fontanelle was depressed and her oral mucosa was dry. Blood tests show the following: Blood pH: 7.56, K+: 3.31 meq/(low). Na 157 mear high Mary was admitted. She was given an oral electrolyte solution. After an hour Mary was still vomiting. The doctors decided to administer intravenous fluids a. List the possible signs of dehydration in a baby Why is Mary's age a concern? b. Based on the findings of the lab tests, explain why Mary's life could be at risk c.Explain why the doctors gave Mary initially an electrolyte solution rich in sodium and glucose and not just plain water.
After an hour Mary was still vomiting. The doctors decided to administer intravenous fluids:
a. Possible indicators of infant dehydration include:
reduced urine production or urine that is darker in color.
dry lips and mouth
Sunken fontanelles (the baby's head's soft patches)
crying but not shedding any tears
oral mucosa (inside the mouth) that is dry or sticky.
Easily irritated or becoming fussier
b. Mary's age is a problem because young children and newborns are more prone to dehydration. They can have rapid fluid loss and imbalances since they have lower body masses and higher metabolic rates.
c. According to the results of the laboratory tests, Mary may have a disorder called metabolic alkalosis that puts her life in danger. An imbalance in the body's acid-base levels, alkalosis, is indicated by blood pH of 7.56, which is alkalosis.
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QUESTION 2 3. Identify the muscle indicated by the black arrow. Identify one synergist of muscle indicated by the red arrow. 4.
The muscle indicated by the black arrow is the rectus femoris muscle. The rectus femoris muscle is one of the four quadriceps muscles that extends knee and hip.
It is the only quadriceps muscle that crosses the hip joint, and so it has a dual function, acting as both a knee extensor and a hip flexor. The rectus femoris arises from the anterior inferior iliac spine (AIIS) and the groove of the acetabulum in the pelvic bone of the hip. It merges with the other three quadriceps muscles — the vastus lateralis, vastus medialis, and vastus intermedius — to attach to the patella via the quadriceps tendon.
This tendon then attaches to the tibia through the patellar ligament, where it helps to maintain the patella in place and helps to stabilize the knee joint.Synergists muscles are the muscles that work together to move the body part in the same direction. The synergist of the muscle indicated by the red arrow is iliopsoas. It is a group of muscles that work together to flex the hip and they are the iliacus and the psoas major. These two muscles have different origins but they both merge at the level of the hip to form the iliopsoas.
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what is phenotype, homozygous, and heterozygous in a kids definition?
Genetics is a field of study in Biology that explores how traits are inherited and expressed in living organisms, including humans, animals, and plants. Knowing key terminology can help us deepen our understanding of the topic.
Phenotype: Refers to the observable or physical traits of an organism. For example, if we are looking at a human who is tall and has black hair, we can say that the phenotype for that human is tall for the height gene and black for hair color.
Homozygous: When an individual has two identical copies of a gene for a particular trait. If homozygous, the genes inherited from the mother and father are exactly the same. For example, if T = tall and t= short, a homozygous individual would be either TT or tt for their height gene.
Heterozygous: When an individual has two different copies of a gene for a particular trait. If heterozygous, the genes inherited from the mother and father will be different. For example, if B = blue hair and b = brown hair, a heterozygous individual would have Bb for their hair color gene.
It typically takes for CHO to be digested, absorbed, and stored as glycogen. Select one: a. 1 to 4 minutes b. 5-10 minutes c. 1 to 4 hours d. 5 to 10 hours
It typically takes around 1 to 4 hours for CHO to be digested, absorbed, and stored as glycogen.
CHO or carbohydrate is an important source of energy for the human body. When consumed, it undergoes digestion, absorption, and storage. The time required for CHO to be digested, absorbed, and stored as glycogen is typically: Option c: 1 to 4 hours
Explanation: After the consumption of carbohydrates, the enzymes in the mouth and small intestine help in its breakdown to glucose. Glucose is then absorbed from the small intestine into the bloodstream, where it is transported to the liver and muscles. These organs store glucose in the form of glycogen. Glycogen is stored until it is needed by the body for energy purposes.This process of digestion, absorption, and storage takes around 1 to 4 hours.
Thus, option c is the correct answer.
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yelshanskaya, m., sobolevsky, a.i. structural insights into function of ionotropic glutamate receptors. submitted.
Yelshanskaya and Sobolevsky conducted a research study on the ionotropic glutamate receptors in order to gain structural insights into their function.
The study conducted by Yelshanskaya and Sobolevsky was aimed at gaining structural insights into the function of ionotropic glutamate receptors. The researchers utilized X-ray crystallography and cryo-electron microscopy to determine the structure of these receptors. The study found that the ionotropic glutamate receptors are heterotetramers, consisting of four subunits that form a ligand-gated ion channel.
The subunits were found to be composed of three distinct domains: the extracellular domain, the transmembrane domain, and the intracellular domain. The extracellular domain was responsible for the binding of glutamate, while the transmembrane domain formed the ion channel. The intracellular domain played a role in the activation and regulation of the receptor. These structural insights provided a better understanding of the function of ionotropic glutamate receptors and may have implications for the development of new drugs for neurological disorders.
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Complete question is:
Yelshanskaya, m., Sobolevsky, a.i. structural insights into the function of ionotropic glutamate receptors. submitted.
An excitatory postsynaptic potential (EPSP) is associated with ________.
Group of answer choices
A. a change in potassium ion permeability
B. hyperpolarization
C. depolarization
D. lowering the threshold for an action potential to occur
E. repolarization
An excitatory postsynaptic potential (EPSP) is associated with depolarization. The answer is (C).
A postsynaptic potential (PSP) is a graded potential in the receiving neuron that is evoked by the arrival of a neurotransmitter at a chemical synapse. When the potential is depolarizing and makes the neuron more likely to fire, it is called an excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potentials (EPSPs) result from an influx of positively charged ions (usually Na+ or Ca2+) into the neuron or an outflow of negatively charged ions (usually Cl–).
As a result, EPSPs are depolarizing events that boost the likelihood of an action potential being generated in the neuron. The arrival of an action potential at a presynaptic terminal causes a rise in intracellular calcium ion concentration, which induces the synaptic vesicles in the presynaptic terminal to exocytose their neurotransmitter content. Therefore, the answer is (C).
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Damage to specific regions of the cerebral cortex, such as through a stroke, can result in specific losses or function. Take a look at the pictures below. Which lobe is affected by the stroke? Next, Name the typical signs and symptoms of a stroke?
The lobe that is affected by the stroke is the temporal lobe. The typical signs and symptoms of a stroke are numbness, weakness, or paralysis of the face, arm, or leg, particularly on one side of the body.
What is a stroke?A stroke is a disease that occurs when blood flow to the brain is disrupted. When this happens, brain cells do not receive enough oxygen or nutrients and begin to die. Stroke is a leading cause of death and disability worldwide. There are two types of strokes: Ischemic stroke- It is caused by a blockage in a blood vessel in the brain. Hemorrhagic stroke- It occurs when a blood vessel in the brain ruptures or leaks.
The cerebral cortex is the outer layer of the brain. It is responsible for a variety of functions, including movement, sensation, perception, and cognition. It is divided into four main lobes: the frontal lobe, parietal lobe, temporal lobe, and occipital lobe. The damage to specific regions of the cerebral cortex, such as through a stroke, can result in specific losses of function.
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Which of the following did you include in your
answer? Check all that apply.
h
body rejects transplants because it
recognizes them as foreign
lymphocytes attack the new organ
tissue typing measures antigens on tissue
donor organ for compatibility
immunosuppressants disrupt the replication
process of lymphocytes that produce
antibodies and makes the immune system
less effective
DONE✔
The body rejecting transplants because it recognizes them as foreign is related to the concept of organ rejection in transplantation.
Lymphocytes attacking the new organ is also associated with the immune response against the transplanted tissue.
Tissue typing measures antigens on tissue to determine compatibility between the donor organ and the recipient.
Immunosuppressants are medications that disrupt the replication process of lymphocytes that produce antibodies and weaken the immune system's response to prevent rejection.
1. The complete development of chick is in a. 19−20 th day 2. b. 18−19th day 3. c. 18−20th day 4. d. 20−21 st day The temperature of the poultry house for 5 -week-old chickens raised on deep litter should be a. 35−38 ∘C b. 40−50 ∘C C. 18−22 ∘C d. 27−32 ∘C
The complete development of a chick typically occurs in 19-20th day. This refers to the incubation period required for the fertilized egg to develop into a fully formed chick inside the eggshell. The Correct option is a .
During this period, the embryo undergoes various stages of development, including the formation of vital organs, skeletal structure, feathers, and other essential features necessary for hatching. On the 19th to 20th day, the chick is ready to hatch and break out of the eggshell.
The temperature of the poultry house for 5-week-old chickens raised on deep litter should be 18-22 ∘C. The Correct option is c. Deep litter refers to a system where chickens are raised on a thick layer of bedding material, such as wood shavings or straw.
Maintaining the temperature within the range of 18-22 ∘C is important to ensure the well-being and optimal growth of the chickens at this stage. Temperatures below this range can make them feel cold and hamper their growth, while temperatures above this range can cause heat stress and negatively impact their health. Therefore, providing a temperature range of 18-22 ∘C is considered suitable for 5-week-old chickens raised on deep litter. The Correct option is a
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Fil in the bianks of the following sentences. The dartos and cremaster muscles heip to maintain Ideal testicular temperature. The idealtemperature is sightty ____ than body temperature. If the outside tenperature is too cold, the dartos and cremaster will _____ Which will cause the testes to move the body ____ If the outside temperature is too warm, the dartos and cramaster will which will cause the testes to move ____ the body.
The dartos and cremaster muscles help to maintain ideal testicular temperature. The ideal temperature is slightly lower than the body temperature. If the outside temperature is too cold, the dartos and cremaster will contract, which will cause the testes to move the body closer, if the outside temperature is too warm, the dartos and cremaster will relax, which will cause the testes to move away from the body.
Both the cremaster and dartos muscles are vital for regulating the temperature of the testes and keeping them at the appropriate temperature. This is important because if the testes become too cold or too warm, it can damage or kill sperm, which can result in infertility.
It's important to note that temperature regulation is not the only factor that affects sperm production. Hormones, nutrition, and overall health are all essential to healthy sperm production and fertility. In summary, the dartos and cremaster muscles play a vital role in maintaining ideal testicular temperature, which is critical for healthy sperm production.
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Explain the corrective treatment for the deficiency of two nutrients and how the treatments relieves the symptoms of each deficiency.
The deficiency of two nutrients can be treated with the help of some corrective measures, which is by increasing the intake of calcium and iron.
1) Calcium is a mineral that is essential for maintaining strong and healthy bones. Calcium deficiency can lead to weakened bones and increased risk of fractures.Treatment for calcium deficiency involves taking calcium supplements, eating calcium-rich foods, and increasing vitamin D intake. These treatments can help relieve the symptoms of calcium deficiency and improve bone health.
2) Iron is an essential nutrient that helps produce red blood cells, which carry oxygen throughout the body. Iron deficiency can lead to anemia, which can cause fatigue, weakness, and other symptoms. Treatment for iron deficiency involves taking iron supplements, increasing iron-rich foods in the diet, and consuming foods that enhance iron absorption.
These treatments can help relieve the symptoms of iron deficiency and improve overall health. Corrective treatment for calcium deficiency can relieve symptoms by increasing the amount of calcium in the body. Calcium supplements can help restore calcium levels in the body, while vitamin D supplements can help the body absorb calcium better. Eating calcium-rich foods can also help increase calcium levels and relieve symptoms.
Corrective treatment for iron deficiency can relieve symptoms by increasing the amount of iron in the body. Iron supplements can help restore iron levels in the body and reduce symptoms of anemia. Consuming iron-rich foods, such as red meat and leafy greens, can also help increase iron levels and relieve symptoms. Additionally, consuming vitamin C-rich foods can help enhance iron absorption.
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A pheochromocytoma is a tumor located in the medulla of the adrenal gland. This tumor results in excessive release of hormones from the adrenal medulla. Based on your understanding of the adrenal glands, what symptoms might patients with this kind of tumor have?
Patients with a pheochromocytoma may experience symptoms such as hypertension (high blood pressure), palpitations (rapid heartbeat), sweating, headache, anxiety, and tremors due to the excessive release of adrenaline and noradrenaline from the adrenal medulla.
The adrenal medulla is responsible for producing and releasing adrenaline (epinephrine) and noradrenaline (norepinephrine), which are hormones involved in the body's stress response. A pheochromocytoma is a tumor that develops in the medulla of the adrenal gland, causing it to produce excessive amounts of these hormones. As a result, patients with this tumor may experience symptoms related to increased levels of adrenaline and noradrenaline.
The excess release of these hormones can lead to persistent hypertension, which can be severe and difficult to control. Patients may also experience palpitations or a rapid heartbeat due to the stimulating effects of adrenaline on the heart. Sweating, headache, anxiety, and tremors are common symptoms associated with increased sympathetic activity caused by excessive hormone release.
It's important to note that symptoms can vary in severity and may occur episodically, depending on the tumor's activity. Proper diagnosis and management of pheochromocytoma involve medical evaluation, imaging studies, and surgical removal of the tumor to alleviate symptoms and prevent complications related to hypertension and hormone imbalances.
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1. compare the three levels of function of dental practice management software and discuss their application
Dental practice management software operates at three levels of function: administrative, clinical, and financial.
Administrative Function: At the administrative level, dental practice management software facilitates tasks related to appointment scheduling, patient registration, insurance verification, and billing. It streamlines front desk operations, improves patient communication, and helps manage patient records efficiently. Administrative features also include generating reports and managing inventory. This level of function enhances practice organization, workflow, and patient management.Clinical Function: The clinical level of dental practice management software focuses on supporting clinical workflows and patient care. It enables practitioners to document patient treatment plans, chart dental conditions, and track treatment progress. Clinical features may include digital imaging integration, treatment notes, prescription management, and communication tools for collaboration with other healthcare providers. This level of function enhances the clinical efficiency, accuracy, and quality of care provided to patients.Financial Function: The financial level of dental practice management software encompasses tasks related to financial management and accounting. It includes features for billing, insurance claims processing, payment tracking, and financial reporting. This level of function helps streamline revenue cycles, monitor practice finances, and ensure accurate and timely reimbursements. Financial features also support managing patient balances, creating payment plans, and analyzing practice profitability.By operating at these three levels of function, dental practice management software optimizes administrative tasks, supports clinical workflows, and facilitates financial management within dental practices. Its comprehensive application improves overall practice efficiency, productivity, and patient satisfaction.
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During the flye exericse, When the hands are being separated,
what type of muscular contraction is taking place at the shoulder
(glenohumeral) joint?
During the flye exercise, the type of muscular contraction taking place at the shoulder (glenohumeral) joint when the hands are being separated is eccentric contraction.
During the flye exercise, the movement involves abduction of the arms away from the midline of the body, which is controlled by the muscles of the shoulder joint. Eccentric contraction occurs when the muscle lengthens while generating tension. In this case, as the hands are being separated, the muscles responsible for shoulder abduction, such as the deltoids and pectoralis major, are contracting eccentrically to control the movement and decelerate the arms. This type of contraction helps in controlling the movement and preventing excessive stress on the joint. Therefore, the answer is ccentric contraction.
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Which of the following passes through the sarcoplasm, causing the sarcoplasmic reticulum to open its "gates"? a. Sodium b. Calcium c. Action potential d. ATP
The following statement about sarcoplasmic reticulum (SR) is true: Sarcoplasmic reticulum releases calcium ions into the sarcoplasm, which then binds to troponin and causes muscle contraction. The answer is (B).
Calcium passes through the sarcoplasm, causing the sarcoplasmic reticulum to open its "gates". The sarcoplasmic reticulum is a specialized organelle present in muscle cells.
This organelle stores calcium ions. When the muscle cell is stimulated, a series of events happen and the sarcoplasmic reticulum releases calcium ions into the sarcoplasm. These calcium ions then bind to troponin and cause muscle contraction. Therefore, the correct option is (b) calcium.
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explain the relationship between the hypothalamus and hypophysis
glands. provide one example showing that relationship.
The hypothalamus and the hypophysis glands have an essential relationship. The hypothalamus is responsible for controlling various hormone functions in the human body.
The hypophysis gland, also known as the pituitary gland, is located at the bottom of the hypothalamus and is responsible for secreting many hormones, which are under the control of the hypothalamus.The hypothalamus and the hypophysis gland are connected through a complex system of blood vessels called the hypophyseal portal system.
The hypophyseal portal system is responsible for carrying the hypothalamus' hormones to the hypophysis gland, where they can stimulate the release of other hormones. The hypophysis gland, in turn, secretes hormones that regulate many different functions in the body, including growth, reproduction, and stress response .One example that demonstrates this relationship is the release of growth hormone.
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We discussed fish, amphibian, and mammalian hearts, but didn’t spend much time on reptiles and birds. Please compare and contrast the anatomy of the heart in
a) most reptiles (turtles, snakes, lizards)
b) crocodiles
c) birds
d) mammals
Draw the basic template of dorsal aorta, ventral aorta, and six aortic arches, along with drawings showing the modified patterns of aortic arches in a-d above.
The anatomy of the heart in reptiles, crocodiles, birds, and mammals differ in various aspects. Reptiles, such as turtles, snakes, and lizards, have a three-chambered heart with two atria and one ventricle. The ventricle is partially divided, allowing for some separation of oxygenated and deoxygenated blood. Crocodiles, on the other hand, have a four-chambered heart similar to mammals and birds. They have two atria and two completely separated ventricles, ensuring complete separation of oxygenated and deoxygenated blood.
Birds have a unique cardiac anatomy compared to other animals. They possess a four-chambered heart like mammals and crocodiles, but with certain modifications to support their high metabolic demands. Birds have relatively large hearts, with thicker walls in their ventricles. They also have a large and muscular left ventricle, allowing for efficient pumping of oxygenated blood to meet the demands of flight.
Mammals, including humans, have a four-chambered heart with two atria and two ventricles. The left and right sides of the heart are completely separated, preventing mixing of oxygenated and deoxygenated blood. Mammalian hearts are well-adapted for efficient circulation, with a strong left ventricle responsible for pumping oxygenated blood throughout the body.
In terms of the basic template of the dorsal aorta, ventral aorta, and aortic arches, reptiles have a pattern where blood is pumped from the ventricle to the aorta, and then to the systemic circulation. Crocodiles have a similar pattern to mammals, where the ventricles pump blood to the pulmonary and systemic circulations simultaneously. Birds have a more complex pattern with multiple aortic arches, which facilitates their high metabolic rate and the unique demands of flight. Mammals have a simpler pattern, with the ventricles pumping blood to the pulmonary and systemic circulations separately.
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Which of the following is not a characteristic of urine a. unsterile b. contains urochrome c. pH of 6 d. aromatic
Option C: pH of 6 is not a characteristic of urine, because urine is typically slightly acidic, with a pH range of 3.0 to 5.0.
Urine can range in color from pale yellow to amber, depending on factors such as hydration levels, diet, and certain medications or medical conditions. The pigment responsible for the yellow color of urine is called urochrome.
Water, waste materials, and different dissolved compounds make up the majority of urine. It has metabolic waste materials like urea, creatinine, and uric acid in it. It also contains various components that may be present based on a person's health and diet, including electrolytes like sodium, potassium, and chloride ions.
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Describe how fed-batch fermentation can increase the yield of a recombinant protein of your choice. What technologies have been used to successfully purify this recombinant protein and outline the principles of their operation?
Fed-batch fermentation is a batch culture of microorganisms with an additional feeding of a nutrient solution to the culture medium to maintain a constant nutrient concentration.
Fed-batch fermentation can increase the yield of a recombinant protein of your choice in the following ways:i. By maintaining a nutrient level in the growth medium.ii. By extending the logarithmic growth phase of the microorganism.iii. By increasing cell density. All these factors lead to increased productivity. There are various technologies used to purify recombinant proteins. The technologies include but are not limited to: i. Affinity chromatography ii. Ion-exchange chromatography iii.
Hydrophobic interaction chromatography iv. Gel filtration chromatography These technologies are based on the different physical and chemical properties of proteins like molecular weight, charge, hydrophobicity, and specific binding properties. Affinity chromatography Affinity chromatography is a chromatographic method that exploits the unique binding characteristics of proteins. It uses a solid phase consisting of a matrix covalently linked to a specific ligand. When a protein sample is passed over the matrix, the protein will bind to the ligand, while other molecules are washed away.
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Lectures 16 – Cardiovascular System - Heart:
What are the 4 chambers of the heart? Slide 4
Know the 4 valves of the heart. Slide 5
Know the main blood vessels entering and exiting the heart. Slide 6
You should know which chambers these vessels exit and enter. What determines whether a blood vessel is called an artery or a vein?
Which side of the heart pumps blood to the lungs (pulmonary circuit)? Which side pumps blood to the rest of the body (systemic circuit)? Slide 9-12
What’s the definition of cardiac output? What’s the formula to calculate cardiac output? Slide 14
If given stroke volume and heart rate, be able to calculate cardiac output.
What’s stroke volume? What’s the formula to calculate stroke volume? Slide 26-30
Understand how the Autonomic nervous system affects cardiac output. Slide 19-22
What effect does the sympathetic nervous system have on heart rate? Stroke volume? Which neurotransmitter is involved in this response?
What effect does the parasympathetic nervous system have on heart rate? Which neurotransmitter is involved in this response?
Cardiac Cycle (for a refresher watch the video on Slide 31)
What is happening during atrial diastole? Atrial systole? Ventricular diastole? Ventricular systole?
Understand that a pressure gradient is what allows the blood to flow from one chamber to another. For example, once pressure in the atria is higher than the pressure in the ventricles, blood will flow from the atria into the ventricle.
Clinical Connections Slide 35-41
What is myocardial ischemia? How does this differ from myocardial infarction?
What is the difference between ischemia and hypoxia?
What is the difference between valve insufficiency vs valve stenosis?
What is auscultation? What does the sound "Lubb" refer to? How about "Dubb"
What is congestive heart failure? What occurs if the left-side of the heart fails first? What occurs if the right-side of the heart fails first?
-The 4 chambers of the heart are the left atrium, left ventricle, right atrium, and right ventricle.
-The 4 valves of the heart are the tricuspid valve, mitral (bicuspid) valve, pulmonary valve, and aortic valve.
-The main blood vessels entering the heart are the superior and inferior vena cava (entering the right atrium) and the pulmonary veins (entering the left atrium).
-Arteries carry oxygenated blood away from the heart, while veins carry deoxygenated blood toward the heart.
-The right side of the heart pumps blood to the lungs (pulmonary circuit), and the left side pumps blood to the rest of the body (systemic circuit).
-Cardiac output is the amount of blood pumped by the heart per minute. The formula is cardiac output = stroke volume x heart rate.
-Stroke volume is the amount of blood ejected by the heart with each contraction.
-The sympathetic nervous system increases heart rate and stroke volume, involving the neurotransmitter norepinephrine.
-The parasympathetic nervous system decreases heart rate, involving the neurotransmitter acetylcholine.
-During atrial diastole, the atria are relaxed and filled with blood. Atrial systole is the contraction of the atria, ventricular diastole is the relaxation of the ventricles, and ventricular systole is the contraction of the ventricles.
-A pressure gradient allows blood to flow from one chamber to another based on differences in pressure.
-Myocardial ischemia is reduced blood flow to the heart, while myocardial infarction refers to tissue death.
-Ischemia refers to inadequate blood supply, while hypoxia refers specifically to low oxygen levels. Valve insufficiency is improper closure causing blood leakage, while valve stenosis is the narrowing or constriction of a valve.
-Auscultation is listening to body sounds, with "Lubb" referring to the first heart sound (AV valve closure) and "Dubb" to the second heart sound (semilunar valve closure).
-Congestive heart failure is the heart's inability to pump effectively, with left-side failure causing pulmonary congestion and right-side failure causing systemic congestion.
The 4 valves of the heart are:
- Tricuspid valve (between the right atrium and right ventricle)
- Pulmonary valve (between the right ventricle and pulmonary artery)
- Mitral valve, also known as the bicuspid valve (between the left atrium and left ventricle)
- Aortic valve (between the left ventricle and aorta)
The main blood vessels entering and exiting the heart are:
- Superior and inferior vena cava (entering the right atrium)
- Pulmonary veins (entering the left atrium)
- Pulmonary artery (exiting the right ventricle)
- Aorta (exiting the left ventricle)
Arteries carry oxygenated blood away from the heart to the tissues, while veins carry deoxygenated blood back to the heart. The distinction is based on the direction of blood flow and oxygenation levels.
Stroke Volume = End Diastolic Volume (EDV) - End Systolic Volume (ESV)
The sympathetic nervous system increases heart rate and stroke volume. It releases norepinephrine (noradrenaline) as the neurotransmitter involved in this response.
- During atrial diastole, the atria are relaxed and filled with blood.
- During atrial systole, the atria contract to push blood into the ventricles.
- During ventricular diastole, the ventricles are relaxed and filling with blood.
- During ventricular systole, the ventricles contract to pump blood out of the heart.
Valve insufficiency (regurgitation) occurs when a valve doesn't close properly, causing blood to leak backward. Valve stenosis occurs when a valve becomes narrowed or constricted, restricting the blood flow through the valve.
Auscultation is the process of listening to internal body sounds using a stethoscope. The sound "Lubb" refers to the first heart sound (S1), which is caused by the closure of the atrioventricular valves (tricuspid and mitral/bicuspid valves). The sound "Dubb" refers to the second heart sound (S2), which is caused by the closure of the semilunar valves (pulmonary and aortic valves).
Congestive heart failure is a condition where the heart is unable to pump blood effectively, resulting in fluid accumulation and congestion in various parts of the body. If the left side of the heart fails first, it can lead to pulmonary congestion and fluid accumulation in the lungs, causing shortness of breath and pulmonary edema. If the right side of the heart fails first, it can cause systemic congestion, leading to fluid accumulation in the peripheral tissues, abdomen, and lower extremities.
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Control of cavity solitons and dynamical states in a monolithic vertical cavity laser with saturable absorber
The research discusses the control of cavity solitons and dynamical states in a vertical cavity laser with saturable absorber.
The article is a research that was conducted to analyze the control of cavity solitons and dynamical states in a monolithic vertical cavity laser with saturable absorber. The study focused on the effects of various parameters such as injection current, absorber bias, and absorber saturation on the laser performance, soliton control, and dynamics. The authors employed several techniques such as optical injection, bistability, and switching to investigate the lasing modes, patterns, and stability regions of the cavity solitons.
They discovered that the cavity solitons could be stabilized or destabilized by varying the bias and saturation levels of the absorber. The results of this research provide insights into the design and optimization of high-performance laser systems for use in optical communication, sensing, and imaging applications.
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What structure does the proximal tubule lead to?
O distal tubule
O intermediate tubule
O glomerulus
O renal corpuscle
O collecting tubule
QUESTION 56
Which of the following are epithelial cells?
O gustatory cells
O Purkinje cells
O pericytes
O goblet cells
O olfactory cells
QUESTION 57
Which of the following lists have all structures that match with the corresponding structure underlined at the end?
O angiotensin I, anglotensin Il, renin, juxtaglomerular cells : liver
O stratum functionalis, stratum vasculare, internal os : oviduct
O axoneme, microtubules, acrosome, flagellum : ovum
O medullipin I, medullipin Il, antihypertensive action : renal medulla
O crystalloid of Charcot-Bottcher, crystals of Rienke, tunica albugenia : prostate
QUESTION 58
Which of the following is true about the renal medullary interstitium and the counter current multiplier mechanism?
O medullary interstitium maintains a relatively very low concentration of NaCl
O descending intermediate tubule is freely permeable to solutes and impermeable to water
O ascending intermediate tubule Is permeable to water and actively retains Nacl
O collecting duct in deep medulla are impermeable to urea
O vasa recta functions as counter current exchangers
QUESTION 59
Which of the following lists have cells or products that match with the corresponding cells or products underlined at the end?
O alpha, beta and delta cells : cells of exocrine pancreas
O follicular cells, paratollicular cells, calcitonin, thyroglobulin : cells of parathyroid gland
O hormone, Intracellular receptor, binding with DNA : testosterone
O chief cells, oxyphil cells, parathyroid hormane t cells of pineal gland
O epinephrine, norepinephrine, chromaffin cells : sells In adrenal zona reticularis
Question 56: The proximal tubule leads to the distal tubule.
Question 57: The epithelial cells are gustatory cells, olfactory cells, and goblet cells.
Question 58: The true statement is that vasa recta functions as counter-current exchangers.
Question 59: The cells or products that match are alpha, beta and delta cells: cells of the exocrine pancreas.
The proximal tubule leads to the distal tubule, which is the correct answer to question 56. Epithelial cells are found in various tissues and their function is to protect and line the surfaces of organs and structures.
In question 57, the epithelial cells mentioned are gustatory cells, olfactory cells, and goblet cells.
The vasa recta, which are specialized capillaries in the kidney, function as counter-current exchangers, allowing for the exchange of substances between the blood vessels and the surrounding renal medullary interstitium, as stated in question 58.
Lastly, in question 59, the cells or products that match are alpha, beta, and delta cells, which are found in the exocrine pancreas.
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During a cardiac cycle, O The right side of heart contracts before the left side of 1 O The right ventricle contracts before the left ventricle O The left atrium contracts before the right atrium O The atria contract before the ventricles
During a cardiac cycle, the atria contract before the ventricles. The electrical impulses generated by the sinoatrial (SA) node travels through the atria which initiates their contraction. This is called atrial systole. At this point, the ventricles are relaxed, filling with blood that is returned to the heart through the venous circulation.
The right and left atria contract together while the right and left ventricles contract together. During ventricular systole, the right ventricle contracts before the left ventricle. This is because the right ventricle only has to pump blood through the pulmonary valve into the pulmonary circulation (lungs) while the left ventricle pumps blood through the aortic valve into the systemic circulation.
The cardiac cycle is divided into two phases: diastole and systole. Diastole is when the heart is relaxed and filling with blood. Systole is when the heart is contracting and ejecting blood. During diastole, the heart is filling with blood and the atria are in diastole while the ventricles are in systole.
In conclusion, the atria contract before the ventricles, the right ventricle contracts before the left ventricle, the right and left atria contract together, and the right and left ventricles contract together. During the cardiac cycle, the heart undergoes a series of electrical and mechanical events that work together to pump blood throughout the body.
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What is carrying capacity?
the maximum number of species that can live together in an area
the maximum population that can be supported in an area
the maximum population that can reproduce in an area
the maximum number of predators that live in an area
Answer:
Explanation:
Maximum population that can be supported in an area (definition)
18. Assuming that brown eyees (B) is dominant to blue eyee (b): you come across a situation where all babies produced from one mating event have brown eyee. If we know one parent has the allele combonation (bb), what must be the allele comibination of their mate?
A. Bb
B. BB
C. bb
28. Assuming that brown eyes (B) is dominant to blue eyes (b) which of the following combinantions of alleles would be present in a blue-eyed individual?
A. Bb
B. BB
C. bb
37. glomerular filtration rate is regulated by many mechanics, two of the mechanisms affect GFR by constricting the afferent arteriole. What effect does constricting the afferent arteriole have on GFR?
A. Decreases
B. stays the same
C. Increases
The allele combination of the mate must be Bb.
When all babies produced from a mating event have brown eyes, and one parent has the allele combination (bb), the other parent must have the allele combination Bb. This is because brown eyes (B) is dominant to blue eyes (b).
In order for all babies to have brown eyes, they must receive the dominant allele (B) from one parent. Since the other parent has the genotype bb, they can only pass on the recessive allele (b) to their offspring.
In this scenario, the parent with the genotype bb does not possess the dominant brown eye allele (B), so they cannot pass it on to their offspring. The allele combination of Bb in the other parent ensures that the offspring will receive the dominant allele for brown eyes, resulting in all babies having brown eyes.
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word or phrase bank medial temporal lobes. caudal Head pons lateral eye movement sciatic nerve taste sensation Midbrain 31 pairs inner ears PNS 12 pairs medullar oblongata fibular nerve superior oblique hip joints Medially simultaneously Ischial gluteal upper limbs CNS dorsal root and ventral roots extrinsic eye sensory and motor signals anterior thigh occipital lobes neck taste sensations skeletal muscles crossed extensor rami intrinsic and extrinsic thoracic and abdominopelvic quadricep visceral signals Hearing anterolateral somatosensory cortex encapsulated nerve sense organ motor neuron larynx and pharynx effectors biceps and skin lumbosacral maxillary nerve spinal cord thermoreceptors and nociceptor lateral rectus medial arm the pons and the medullar oblongata nerve plexus mastication in the mouth. sternocleidomastoid abdominal wall and iliopsoas stretch reflex odorant stimuli side opposite 3 types internal and internal Heart optic chiasma nociceptors Foot swallowing somatic motor signals Golgi tendon interceptors interneuron photoreceptors deltoid teres minor exteroceptors thermoreceptors Electromagnetic Afferent triceps brachii anterior forearm develop command abductor anterior special sense vision, and taste two criterial neurological and sensory chemoreceptors multiple synapses Mechanoreceptors tibia monosynaptic stretch thermoreceptors synapses Afferent Eye withdrawer organs
1. The peripheral nervous system connects the body and environment to the…………………………. The PNS detects sensory stimuli and transmit it to the ……………………... The ……………………………. in turn process the sensory information, develop command, and send it via the ……………………….to the PNS effector like muscles and glands.
2. Cranial nerves are attached to structures in the………………. and …………………… regions of the body. These are sensory nerves, the motor nerves and the mixed motor and sensory nerves. There are ………………of cranial nerves named with Roman figures for nerve one to nerve twelve.
3. The trochlear nerve that moves the eye ………………………and inferiorly, originates from the inferior portion of the…………………………, and terminate on the …………………………. muscles of the eye. The oculomotor motor nerve that also move the eye originates from the superior and lateral portions of the ……………………. and terminate on the …………………………………. muscles and smooth muscles of the eye. The vestibulocochlear verve that controls ………………………….and equilibrium, originates from the vestibular and cochlear nerves of the………………., and terminates on nuclei of the cerebellum and……………………………….
4. The optic nerve that carries visual information, originates from the posterior of the………………………., and form an X-shaped structure called……………………., and terminates on the nuclei of the ……………………….and midbrain before it gets to the visual cortex of the…………………………... The olfactory nerve that carries……………………, originates form the olfactory epithelia and terminates on nuclei of the …………………………….
5. The vagus nerve is a mixed nerve that is responsible for the contraction of muscles surrounding the………………………………, originates from the …………………….and sensory receptors from the pharynx, larynx, skin, ears, certain blood vessels of the neck, innervate throat, anterior neck, visceral organs of …………………………… cavities. The glossopharyngeal nerves are mixed nerves responsible for ………………………. movement, originates from the……………………., and sensory receptor of the tongue, pharynx, and round the ears.
6. The facial nerve, which is responsible for facial expressions and other facial muscles, originates from the …………………… and the medullar oblongata and terminates on the facial muscles the provide ……………………. and somatic sensation from the external eye and nasal cavities. The trigeminal nerve has 3 branches, the ophthalmic nerve, the…………………., and the mandibular nerve. Their origin is from between …………………………………………. and innervates the primary ………………………………for facial sensations. The mandibula nerve innervates the muscles for ……………………………
1. The peripheral nervous system connects the body and environment to the CNS. The PNS detects sensory stimuli and transmit it to the CNS. The CNS, in turn, processes the sensory information, develop command, and send it via the motor neuron to the PNS effector like muscles and glands.
2. Cranial nerves are attached to structures in the head and neck regions of the body. These are sensory nerves, the motor nerves, and the mixed motor and sensory nerves. There are 12 pairs of cranial nerves named with Roman figures for nerve one to nerve twelve.
3. The trochlear nerve that moves the eye laterally and inferiorly originates from the inferior portion of the midbrain, and terminate on the superior oblique muscles of the eye. The oculomotor motor nerve that also moves the eye originates from the superior and lateral portions of the midbrain and terminate on the extrinsic eye muscles and smooth muscles of the eye. The vestibulocochlear verve that controls hearing and equilibrium originates from the vestibular and cochlear nerves of the inner ears, and terminates on nuclei of the cerebellum and midbrain.
4. The optic nerve that carries visual information originates from the posterior of the eye and form an X-shaped structure called optic chiasma, and terminates on the nuclei of the thalamus and midbrain before it gets to the visual cortex of the occipital lobes. The olfactory nerve that carries odorant stimuli originates from the olfactory epithelia and terminates on nuclei of the temporal lobes.
5. The vagus nerve is a mixed nerve that is responsible for the contraction of muscles surrounding the larynx and pharynx, originates from the medulla oblongata, and sensory receptors from the pharynx, larynx, skin, ears, certain blood vessels of the neck, innervate throat, anterior neck, visceral organs of thoracic and abdominopelvic cavities. The glossopharyngeal nerves are mixed nerves responsible for swallowing movement, originates from the medulla oblongata, and sensory receptor of the tongue, pharynx, and round the ears.
6. The facial nerve, which is responsible for facial expressions and other facial muscles, originates from the pons and the medulla oblongata and terminates on the facial muscles that provide somatic motor signals and sensory signals from the external eye and nasal cavities. The trigeminal nerve has 3 branches, the ophthalmic nerve, the maxillary nerve, and the mandibular nerve. Their origin is from between the pons and the medulla oblongata and innervates the primary sensory and intrinsic and extrinsic muscles for facial sensations. The mandibula nerve innervates the muscles for mastication in the mouth.
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16) The success of surgical treatment of cerebral palsy (CP) patients can be assessed by analysis of pre- and post-surgery A) 3D spinal shapes B) EEG patterns during gait C) CAT scans D) joint angle time series during gait E) all of these
The success of surgical treatment of cerebral palsy (CP) patients can be assessed by the analysis of pre- and post-surgery.
Hence, the answer to the given question is option E, all of these.
Cerebral palsy (CP) is a group of neurological disorders that affect a person's muscle control, posture, and movement. It is caused by damage to the brain that occurs before, during, or after birth. The degree of motor function disability in individuals with CP varies widely.CP is usually diagnosed during infancy or early childhood, and treatment includes physical therapy, medications, assistive devices, and, in some cases, surgery. The effectiveness of surgical treatment can be determined by analyzing pre- and post-surgery joint angle time series during gait, EEG patterns during gait, 3D spinal shapes, and CAT scans.
Pre- and post-surgery joint angle time series during gait: This can be used to assess surgical outcomes in patients with CP. The analysis of the angle-time curve can provide information on the effectiveness of the surgery in correcting joint motion and increasing joint range of motion.EEG patterns during gait: EEG patterns during gait can provide information on brain activity and motor control. Changes in EEG patterns after surgery can indicate improvements in motor control and function. 3D spinal shapes: The analysis of spinal shape can provide information on spinal deformities and the effectiveness of surgical interventions in correcting these deformities.
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