Which sequence best describes apoptosis at the G1 checkpoint?

Answers

Answer 1

Answer:

The correct answer is "Cdk/cyclin complex is inhibited→ p53 levels rise → p21 production increase".

Explanation:

The missing options of this question are:

A. p53 levels rise → p21 production increase → Cdk/cyclin complex is inhibited

B. p21 production increase → Cdk/cyclin complex is inhibited→ p53 levels rise

C. Cdk/cyclin complex is inhibited→ p21 production increase → p53 levels rise

D. Cdk/cyclin complex is inhibited→ p53 levels rise → p21 production increase

E. p53 levels rise → Cdk/cyclin complex is inhibited→ p21 production increase

The correct answer is option D. "Cdk/cyclin complex is inhibited→ p53 levels rise → p21 production increase".

Apoptosis is a process at which the cells undergo a programmed death. This mechanisms happens at G1 checkpoint first by the inhibition of Cdk/cyclin complex which causes p53 levels to rise and later, an increment of p21 production. First, a cyclin-dependent kinase inhibitor regulates the inhibition of the Cdk/cyclin complex. This causes p53 levels to rise, since p53 is a direct downstream kinase substrate for CDK. Subsequently, p21 production increase as well since p21 is a inhibitor of cyclin-dependent kinases.


Related Questions


Which three careers use technologies that apply the Doppler effect?

A. Doctor specializing in circulation
B. Military
C. Restaurant worker
D. Meteorologist

Answers

Answer:

Doctor specializing in circulation, meteorologist , military

Explanation:

The three careers that use technologies that apply the Doppler effect are: doctor specializing in circulation; military; and meteorologist, which are in options A, B, and D, respectively.

What is the Doppler effect?

The Doppler effect is a phenomenon that occurs when there is a change in the frequency of a sound wave due to the relative motion between the source of the wave and the observer. The Doppler effect can also be observed with other types of waves, such as light waves, and is used in a variety of technologies to measure the speed, direction, and velocity of objects.

Hence, three careers that use technologies that apply the Doppler effect are: doctor specializing in circulation; military; and meteorologist, which are in options A, B, and D, respectively.

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The energy used to pump hydrogen ions from the mitochondrial matrix across the inner membrane and into the intermembrane space is derived from:________

a. ATP hydrolysis
b. reactions in the electron transport chain
c. decreasing the pH in the mitochondrial matrix
d. splitting water to form oxygen and protons

Answers

Answer:

b. reactions in the electron transport chain

Explanation:

Oxidative phosphorylation, which is the process described in this question, is the third stage of cellular respiration which occurs in the MITOCHONDRION of eukaryotic cells. In this stage of oxidative phosphorylation, which encompasses electron transport chain (ETC) and chemiosmosis, ATP is synthesized.

The ATP is synthesized when protons (H+) move from the mitochondrial matrix into the intermembrane space, forming, a proton pump. The series of electron transfers (reactions) that occur in the complexes of the ETC provides the ENERGY to pump the protons/hydrogen ions out of the matrix, which creates the electrochemical gradient required for ATP synthesis with the help of ATP synthase.

please help and would be very appreciated

Answers

It’s to transport oxygen and I believe it’s 2 or 4. Sorry

What color is the eye most sensitive too? What color do the eyes mostly see? What colors do the eyes not see ?

Answers

The eyes is mostly sensitive to a yellowish-green color
The eyes mostly see the colors blue,green and red
The eyes do not see the colors red-green and blue-yellow

Hope this helps

Have a great day/night

The drug 2,4-dinitrophenol (DNP) destroys the proton gradient across the inner mitochondrial membrane. What would be the effect of incubating isolated mitochondria in a solution of DNP

Answers

Answer:

This question lacks options, options are:A) Oxygen would no longer be reduced to water. B) No ATP would be made during transport of electrons down the respiratory chain. C) Mitochondria would show a burst of increased ATP synthesis. D) Glycolysis would stop. E) Mitochondria would switch from glycolysis to fermentation.The correct answer is B)

Explanation:

The main mechanism of ATP production takes place in our mitochondria, which are cellular organelles, and this occurs when molecules of coenzymes or reduced prosthetic groups, coming from the process of catabolism of nutrients, are oxidized with molecular oxygen (which becomes in water), leading to the production of ATP. DNP works by increasing heat production in cells through a process known as decoupling. Dinitrophenol is an ionphoric compound that cuts mitochondrial ATP production circuits. This cessation of ATP production through the mitochondria leads to an increase in metabolic rate (as the substrate is used at a higher rate so that cytosolic ATP can sustain life) and subsequent weight loss.

Matching/Sequencing Activity: Maslow's Hlerarchy of Needs
The labels at the left are examples from different levels of Maslow's Hierarchy of Needs. First, drag each label to the corresponding level of Maslow's Hierarchy. Second, rearrange the levels so that they are in the correct order, with the lowest level of the Hierarchy on the bottom.
Drag the text blocks below into their correct order.
a. relationships with others and giving affection
b. confidence in oneself
c. risk avoidance and protection
d. self-acceptance and expression
e. food and shelter
1. Love and Belongingness______. 2. Physiological Needs____ 3. Safety and Security_____. 4. Self-actualization_____. 5. Self-esteem_____.

Answers

Answer:

Explanation:

1. Matching each label to corresponding level of Maslow's Hierarchy, we have

a. relationships with others and giving affection ------ Love and Belongingness

b. confidence in oneself ------- Self-esteem

c. risk avoidance and protection---Safety and security

d. self-acceptance and expression---- Self-actualization

e. food and shelter-----Physiological Needs

2.rearranging  the levels so that they are in the correct order, with the lowest level of the Hierarchy on the bottom.

Maslow's hierarchy of needs is a psychology theory which  shows and explains human needs in a  five-tier model pyramid in hierarchy  From the top to  the bottom of the hierarchy, we have

1.self-acceptance and expression---- Self-actualization

2.confidence in oneself ------- Self-esteem

3.relationships with others and giving affection ------ Love and Belongingness

4.risk avoidance and protection---Safety and security

5. food and shelter-----Physiological Needs

Maslow's is known for his theory on the Hierarchy of Needs. The answers are below;

The relationships with others and giving affection  falls under Love and Belongingness.The confidence in oneself  falls under  Self-esteem.The risk avoidance and protection  falls under Safety and security.The self-acceptance and expression  falls under Self-actualization.The food and shelter  falls under Physiological Needs.

The rearranging of the level from the Highest to the lowest level are;

Self-actualizationSelf-esteem Love and BelongingnessSafety and securityPhysiological Needs. (Base)

What is Maslow's Hierarchy of Needs used for ?

Maslow's Hierarchy of Needs Helps us and also health practitioner such as nurses establish the hierarchy of needs and priority of care for their patient.

Learn more about Maslow's Hierarchy of Needs from

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Choose the best definition for the vocabulary term: Specificity

Answers

Answer:

The quality of belonging or relating uniquely to a particular subject.

Explanation:

Explanation:

i can explain but where are the points to choose the best definition

Which resource is renewable? coal oil steel wind

Answers

Answer:

Wind is renewable.

Explanation:

The Renewable resources is wind.

What are renewable energy?

Renewable resources are natural materials that they don't diminished. They are in abundance and are not easily exhausted. They normally replenish themselves.

Therefore, The Renewable resources is wind.

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You know that you have a balanced chemical equation when the
a.coefficients of the reactants equal the coefficients of the products.
b.numberofatomsofeachelementinthereactantsequalthatofeachcorrespondingelementinthe products.
c.products and reactants are the same chemicals.
d.subscripts of the reactants equal the subscripts of the products.

Answers

Answer:

The correct answer should be a

What further evidence do we need to diagnose Elisa?

Answers

Answer:

ELISA, using excretory-secretory antigens from infective-stage larvae, is the diagnostic test of choice. In patients whose clinical signs and history suggest visceral toxocariasis, a positive Toxocara ELISA is strong presumptive evidence of Toxocara infection. A rising or falling titer with a twofold difference in a recently ill patient is consistent with visceral toxocariasis

ELISA stands for enzyme-linked immunoassay. It is a commonly used laboratory test to detect antibodies in the blood. An antibody is a protein produced by the body's immune system when it detects harmful substances, called antigens

plants absorb what from the atmosphere through what

Answers

Answer:

they absorb moisture from the air

plants absorb energy from the atmosphere through photosynthesis ?

Why is the action of phagocytes considered a nonspecific response?​

Answers

Answer:

its the second option not 3rd.

D, the other answer is wrong

Please Help
Sex-Linked Disorder

Answers

Explanation:

hemopholia

colour blindness

Movement across the cell membrane that does not require energy is called

Answers

Answer:

It's called passive transport

Explanation:

It's called passive transport because it doesn't use energy like active transport does.

Answer:

Passive transport

Explanation:

This is a  movement of a substances across the membrane without the expenditure of cellular energy. In contrast, active transport is the movement of substances across the membrane using energy from adenosine triphosphate.

sedimentary igneous and metamorphic rocks are all formed in the same way true or false​

Answers

Answer:

False

Explanation:

The way they are formed is in the name. Sedimentary are built from layers of materials being compacted over huge timespans. Igneous are formed as lava or magma cools into a solid material. Metamorphic are rocks that are changed from other types of stone due to high heat and pressure in the Earth.

DNA molecule has 100 cytosine 850 thymine base write the base pair

Answers

It will have 100 Guanine and 850 adenine.

Correct if I’m wrong.

Answer:

cytosine always pairs with guanine and it always have the same molecule

so, if cytosine is 100, guanine is also 100

thymine also has the same number of molecules as adenine cuz it pairs together

so, if thymine is 850, adenine is also 850

total-->200+1700=1900

i hope this helps!

plz give me brainliest

stay safe from the virus

Explanation:

What are the charges both inside and outside of the neuron before you click the stimulate neuron button?

Answers

Answer:

The charges inside and outside of the neuron before receiving a stimulus are negative and positive, respectively, which corresponds to the transmembrane rest potential.

Explanation:

Neuron is the specialized cell of the nervous system in charge of transmitting electrical impulses. The generation of a nerve impulse in the form of an electric current is due to a change in the transmembrane potential.

Outside the neuron cell, electrical charges are predominantly positive, and the ion with the highest concentration is sodium. In the intracellular space, a great quantity of proteins provide negative charge, and there is a predominance of potassium ions. Under these conditions, the ionic channels are closed.

For this reason, a neuron at rest, before receiving a stimulus, presents positive charges on the outside and negative charges on the inside, and the membrane potential in this condition is estimated at a value of -65 mV.

Once a stimulus is produced, the ionic channels open and Na+ ions enter the cytoplasm, exchanging them for K+, which implies a change in the membrane potential which, on reaching the threshold, produces an action potential and the nerve impulse is produced.

Explain the function of the thyroid gland and the hormones it secretes. Include how the release of hormone is regulated and what cells the hormone act on g

Answers

The thyroid gland releases triiodothyronine (T3) and thyroxine (T4). These hormones play an important role in regulation of your weight, energy levels, internal temperature, skin, hair, nail growth, and more. Thyroxine (T4) is produced by the thyroid gland under regulation from the hypothalamus and pituitary gland. T3 is a second thyroid hormone that is produced by the thyroid gland but also in other tissues through deiodination of T4. T3 helps maintain muscle control, brain function and development, and heart and digestive functions.

What type of energy does a ball have when it rolls down a hill?

Answers

Answer: When a ball rolls downhill, the gravitational potential energy of the ball is transformed into motion energy.

Answer:

When a ball rolls downhill, the gravitational potential energy of the ball is transformed into motion energy.

Hope this helps :)

Do you think mankind will ever reach the center of the Earth? How do you think we could get there

Answers

Answer:

May be this can help

But we've never been to the planet's core. We haven't even come close. The central point of the Earth is over 6,000km down, and even the outermost part of the core is nearly 3,000 km below our feet.Aug 13, 2015

Answer:

Explanation:

No,I don't think mankind will reach the center of the Earth because most of the people don't care about others .If there are people who are poor,they don't sometimes care about helping them. We could get there by helping people and understanding their feelings.

To observe a small, living organism, a scientist might use a(an)

Answers

Maybe a microscope I think

Due to the fact that ice is less dense than water inrits liquid form Select one:
a. snow falls to the ground
b. ice storms are very dangerous
c. aquatic life can survive in a pond that has frozen over at the surface
d. cars will hydroplane if one drives too fast on a wet roadway​

Answers

hey i think the answer is A

Acacia ants live in Acacia trees, and attack animals that try to eat the tree. This is an example of:
O mutualism
O communialism
O parasitism
O my nightmare

Answers

D.
That is probably the most scary thing I’ve ever heard...

When nucleotides link together in a series spiraling clockwise they form a

Answers

Nucleotides are joined together by covalent bonds between the phosphate group of one nucleotide and the third carbon atom of the pentose sugar in the next nucleotide. This produces an alternating backbone of sugar - phosphate - sugar - phosphate all along the polynucleotide chain.

Answer:

The nucleotides form a Double Helix (also referred to as a twisted ladder).

Choose a specific site for further study where eutrophication is a problem (such as Chesapeake Bay, the Baltic Sea, or the Gulf of Mexico). List some sources of nitrogen and/or phosphorous to the water body and describe some of the ecological problems due to eutrophication at this specific site.

Answers

Explanation:

Due to the commercial farming activities in the MidWest, fertilizers and pesticides are usually washed away by precipitation and drain into the Gulf of Mexico. These elements (mainly nitrogen and phosphorus) offer much nutrients for algae causing them to thrive into algae blooms. Bacteria then find ‘fodder’ in dead algae breaking them down for energy sources. The bacteria, mostly aerobic, take up most of the oxygen from the water as they thrive. This makes the waters of the Gulf hypoxic hence the other marine organisms such as fishes cannot thrive. Actually, the ecosystem dies and the region is recognized as a' dead zone'.  

Learn More:

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Answer: (Answers may vary.)

Sources of nitrogen and phosphorous in Chesapeake Bay include runoff from agriculture, air pollution from vehicles and power plants, and wastewater from sewage and industry. Ecological problems resulting from the eutrophication include blocking of sunlight to aquatic grasses, stressing fish and shellfish by depleting oxygen, and rising pH, which further stresses fish and makes them susceptible to parasites.

Explanation: edmentum / plato

Some amino acids are both glucogenic and ketogenic. Explain the difference between the two types and why some amino acids can be both g

Answers

Answer:

From the point of view of the type of molecule that is obtained after the degradation of the hydrocarbon skeleton, amino acids can be classified as: glucogenic and ketogenic. The main difference between glucogenic amino acids and ketogenic amino acids is that glucogenic amino acids can be converted to pyruvate or other glucose precursors, while ketogenic amino acids can be converted to acetyl CoA and acetoacetylCoA.

Explanation:

Glucogenic amino acids are amino acids that break down to pyruvate, alpha-ketoglutarate, succinyl Co-A, fumarate, and oxaloacetate and are so named because the synthesis of glucose from these molecules is feasible. Both pyruvate and the Krebs cycle intermediates noted above can be converted to phosphoenolpyruvate and subsequently glucose through gluconeogenesis.Ketogenic amino acids are the amino acids that generate acetyl-CoA or acetacetyl-CoA and are called by this name because they can cause ketone bodies. Since mammals lack the proper enzyme system, these compounds can never be used as precursors for glucose biosynthesis. Of the twenty universal amino acids, fourteen are purely glucogenic and two are purely ketogenic (leucine and lysine). The remaining four (isoleucine, phenylalanine, tryptophan and tyrosine) are glucogenic and ketogenic simultaneously since a part of the hydrocarbon skeleton originates precursors for the biosynthesis of glucose (pyruvate or Krebs cycle intermediates) and the other part acetyl-CoA or acetacetyl -CoA.

What can be done to make a lot of human growth hormone so that it can be used therapeutically?

Answers

Answer: Recombinant human growth hormone

Explanation:

Recombinant human growth hormone can be prepared by combining the gene responsible for production of hormone can be inserted into the bacterial plasmid and then a recombinant DNA forms the bacteria is allowed to be grown in cultures. Then the cultured volume can be exploited to obtain the growth hormone for therapeutic purpose.

Which of the following is an example of how the principle of beneficence can be applied to a study employing human subjects?

Answers

Answer:

Determining that the study has a maximization of benefits and a minimization of risks.

Explanation:

What happens on a cellular level during a organ rejection? Simplified.

Answers

The ability of recipient T cells to recognize donor-derived antigens, called allorecognition, initiates allograft rejection. Once recipient T cells become activated, they undergo clonal expansion, differentiate into effector cells, and migrate into the graft where they promote tissue destruction.

Organ rejection takes place when your body is subjected to a new organ which is a foreign object and attacks it.

What do you mean by Graft rejection?

Graft rejection may be defined as a process in which a transplant recipient's immune system attacks the transplanted organ or tissue.

Xenograft shows high rejection. This is because it involves the transplantation between genetically distinct members of different species.

The process of organ rejection is initiated by T cells which perform the role of the recognization of a transplanted organ.

If these T cells are activated, it may lead to organ rejection by undergoing clonal expansion, and differentiation of the effector cells, which together lead to the obliteration of the tissues.

Therefore, organ rejection takes place when your body is subjected to a new organ which is a foreign object, and attacks it.

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PLIZZZZZ CAN SOMEONE CAN HARLP ME

As Betty waits, she counts the number of waves that pass her during a 10-second period; she counts just 1 She estimates that the distance between crests is 6 meters. Betty sees the perfect wave and begins paddling. She pushes herself up, stands on the surfboard and rides the wave all the way in to shore, a distance of about 60 meters. It takes her about 10 seconds to ride the wave in. Use two methods to calculate the speed of the wave based pn the information presented. Are they the same? Explain how you got your answers.

Answers

Answer: 1. 0.6 m/sec.    2. 6m/sec

Explanation:

Frequency = 0.1/sec wavelength = 6 m

speed = freq x wavelength = 0.6 m/sec

speed = distance/time = 60/10 = 6m/sec

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